chemist measuring solution into test tube

Center for Molecular Analysis of Disease Pathways

The Center for Molecular Analysis of Disease Pathways is an NIH Center of Biomedical Research Excellence (COBRE) focused on the creation and implementation of enabling technologies for the investigation of the genetic, biochemical and physical origins of disease.


Researchers reviewing scientific data in lab

Supporting Research Statewide

The Center for Molecular Analysis of Disease Pathways (CMADP) brings together junior and senior faculty from the physical, biological, and pharmaceutical sciences at the University of Kansas and other academic institutions in Kansas.

What We Do

CMADP's scientific emphasis is on the creation and implementation of enabling technologies that can be employed to identify new therapeutic targets. This includes state of the art methods for gene sequencing, the genetic manipulation of model organisms, custom fluorescent molecular probes for monitoring physiological processes in model organisms, and microfluidic systems for manipulation and monitoring of biochemical pathways.

CMADP capitalizes on existing and evolving expertise in the fields of bioanalytical chemistry, molecular design, genomics and bioengineering at the University of Kansas (KU) and Kansas State University (KSU). The PI, Co-Investigators, research investigators, core directors, mentors, and members of the internal advisory committee represent ten academic departments, six Colleges and Schools, and two Research Centers at KU and KSU. The departments of Biology and Chemistry at KSU are also represented by members of the CMADP's core facility steering committees. The senior faculty members in these departments, schools and centers have a long history of research collaborations and cross-training of graduate students and post-doctoral associates.

Core Laboratories

researcher working at Illumina instrument

Genome Sequencing Core

Next-Generation Sequencing (NGS) technology
Chemist performing an experiment under a hood in a laboratory

Synthetic Chemical Biology Core

Molecular probe synthesis capabilities
Researcher performing experiment in cleanroom while wearing a suit

KU Nanofabrication Facility

Micro/Nanofluidic device design and fabrication

Research reported in this website is supported by an Institutional Development Award (IDeA) from the National Institute of General Medical Sciences of the National Institutes of Health under Award Number P20GM103638. The content is solely the responsibility of the authors and does not necessarily represent the official views of the National Institutes of Health.