NIH’s Public Access Policy:
Information and Tools to Ensure Compliance

Friday, March 29, 2013, 2:00-3:00 p.m.
Simons Auditorium, Simons Labs
2093 Constant Ave., KU west campus, Lawrence

Click here to view a recording of this seminar in Adobe Connect format.

Click here to view/download the PowerPoint for this seminar in pdf format.

For anyone with NIH funding, compliance with the NIH guidelines on public access to publications is critical, especially since the guidelines include plans for NIH to withhold funding for grants which produce publications that do not comply.   You are cordially invited to a seminar hosted by the KU-Lawrence COBREs, and presented by Alicia Reed, Grant Officer, Research and Graduate Studies/KU Center for Research.

  • Abstract:  This seminar will provide information for investigators on the NIH Public Access Policy and how they can ensure compliance with the policy.  Key information will include an overview of the policy, the main steps to compliance, and details on the tools that are available to assist with compliance including Pub Med Central and the National Center for Biotechnology Information bibliographic portal (My NCBI). The presentation will also include details about how to best utilize My MCBI, including its interface with eRA Commons for reporting and how to use the delegate functionality.

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Upcoming Events
Special seminar by Dr. James P. Landers
Commonwealth Professor in Chemistry,
Mechanical Engineering & Pathology
University of Virginia

Wednesday, May 17, 2017 at 3:00pm
Simons Auditorium, HBC, West Campus

"Integrated Microfluidic Systems for Forensic DNA Analysis"
In 2006, we demonstrated that microfluidic technology could provide a ‘lab-on-a-chip’ solution for real-world genetic analysis. Sample-in/answer-out functionality was shown for the detection of bacteria in mouse blood and in a human nasal swab, with a sub-30 minute analytical time for DNA extraction, amplification, electrophoretic separation and detection. We extrapolated these technology developments to the analysis of short tandem repeats (STR) in human DNA; these clinically-insignificant (presumably) tetranucleotide sequences function effectively for statistically-relevant matching in human identification. Our efforts led to the development of a commercializable system designed for implementation in crime labs for STR profiling convicted felons or, in some states, profiling arrestees in booking stations. An intricate but functional microfluidic architecture allowed sample-to-profile to be achieved from a cheek swab in less than 80 minutes, using nanoliter flow control, infrared thermocycling and rapid electrophoretic separation of DNA with 5-color fluorescence detection. We have since demonstrated the fabrication of hybrid microdevices composed of inexpensive polymeric materials, many of these commercial-off-the-shelf. We have designed, built and functionalized fully-integrated DNA analysis chemistry/microfluidics on a rotationally-driven system the size of a compact disc. With this system, DNA can be extracted from a swab, PCR amplified to generate an abundance of DNA fragments of the STR loci, followed by resolution of those fragments in a separation in a 4 cm Leff channel that is complete in <300 sec with a 2-base resolution. The processes that allow for swab in–profile out microfluidics are carried out on an instrument that can be carried in one hand and weighs ~14 lbs, ultimately allowing for facile rapid human identification/screening in the field.
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